On Sample Size Determination for Bioequivalence Studies Based on Confidence Intervals.
نویسندگان
چکیده
منابع مشابه
Confidence Intervals for Lower Quantiles Based on Two-Sample Scheme
In this paper, a new two-sampling scheme is proposed to construct appropriate confidence intervals for the lower population quantiles. The confidence intervals are determined in the parametric and nonparametric set up and the optimality problem is discussed in each case. Finally, the proposed procedure is illustrated via a real data set.
متن کاملSimultaneous Confidence Intervals and Sample Size Determination for Multinomial Proportions
Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available at http://www.jstor.org/about/terms.html. JSTOR's Terms and Conditions of Use provides, in part, that unless you have obtained prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive only for your perso...
متن کاملSample Size Determination for Individual Bioequivalence Inference
Statistical criterion for evaluation of individual bioequivalence (IBE) between generic and innovative products often involves a function of the second moments of normal distributions. Under replicated crossover designs, the aggregate criterion for IBE proposed by the guidance of the U.S. Food and Drug Administration (FDA) contains the squared mean difference, variance of subject-by-formulation...
متن کاملComparing two Formulas of Sample Size Determination for Prevalence Studies
Background and purpose: Sample size and its determination is one of the most important problems in health researches. Calculating sample size for prevalence studies is one of the common questions of sample size topics. Minimum sample size with least complexity is desirable in order to achieve the basic goal of these studies. This study aims to compare two formulas of sample size calculation for...
متن کاملConfidence intervals for the Hurst parameter of a fractional Brownian motion based on finite sample size
In this paper, we show how concentration inequalities for Gaussian quadratic form can be used to propose exact confidence intervals of the Hurst index parametrizing a fractional Brownian motion. Both cases where the scaling parameter of the fractional Brownian motion is known or unknown are investigated. These intervals are obtained by observing a single discretized sample path of a fractional ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 2000
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.31.715